autophagosome

Autophagy induced by aminophylline in peripheral blood T lymphocytes;

氨茶碱诱导T淋巴细胞自噬现象的观察

Induction mechanisms of autophagy and its role in cancer therapy;

自噬的诱导机制及其在肿瘤治疗中的作用

Research Progress on Autophagy Molecule Mechanism;

自噬分子机制的研究进展

A novel path for therapy of neural degeneration diseases is offered by the application of small molecule,which enhances the clearance of aggregate-prone proteins through inducing autophagy.

大量突变和错误折叠的蛋白质在细胞内聚集是神经退行性疾病产生的基础,研究发现一些小分子可以通过引起细胞自噬而降解细胞内聚集的突变蛋白,为治疗神经退行性疾病提供了新的方法。

Autophagy is a common,functionally and evolutionarily preserved p.

但是,关于其细胞自噬基因的研究目前还未见报道。

[Objective] To investigate the function of the hAPG12 in the process of autophagy in yeast, the hAPG12-EGFP fusion gene shuttle vector was constructed and The plasmid constructed above was transformed into the yeast.

结果证实EGFP-hAPG12基因已完全正确亚克隆到pESC-URA中,荧光显微镜观察结果证明EGFP-hAPG12融合蛋白在酵母中成功表达,以诱导培养24h的荧光最强,EGFP-hAPG12定位于酵母的自噬体中。