transcriptional elongation

Evidence showed that Elongator complex plays a crucial role in transcription elongation through chromatin templates; it was the first HAT complex that was found to participate in the transcription elongation.

由6个亚基组成的Elongator复合物是RNA聚合酶II(RNApolymeraseII,RNAPII)全酶的一个重要组成部分,它可以与高度磷酸化的RNAPII相结合,其Elp3亚基具有组蛋白乙酰转移酶(histoneacetyltransferase,HAT)活性,在以染色质为模板的转录延伸中发挥重要作用。

Hexamethylene bis-acetamide-inducible protein(HEXIM)is a newly discovered protein that plays a role in regulation of transcription elongation.

环六亚甲基二乙酰胺诱导蛋白(hexamethylene bis-acetamide-inducible protein,HEXIM)是新近发现的参与转录延伸调控的蛋白质,包括HEXIM1和HEXIM2两种同源物。