Voriconazo

Objective To analyze retrospectively the manifestations and compare the efficacy and safety of micafugin, Voriconazol and Liposomal Amphotericin B in the treatment of invasive fungal infections in patients with hematologic malignancy.

目的:分析恶性血液病合并侵袭性真菌感染的临床特点;评价米卡芬净、伏立康唑与两性霉素B脂质体在治疗恶性血液病合并侵袭性真菌感染的有效性和安全性。

Determination of the Content of Amphotericin B by Means of Ultraviolet Spectrophtonetric Method;

紫外分光光度法测定两性霉素B的含量

Preparation of amphotericin B magnetoliposomes and quality control;

两性霉素B磁性脂质体的制备与质量控制

Preparation and characterization of amphotericin B-polybutylcyanoacrylate nanoparticles;

携载两性霉素B的聚氰基丙烯酸正丁酯纳米粒的制备及特性评价

To establish an RP-HPLC method for determination of the assay and related substance of am- photericin B and liposomal amphotericin B.

目的:建立反相高效液相色谱法测定两性霉素 B 及其脂质体含量与相关物质。