extremely thermophilic bacteria

Cloning Expression and Purification of Heat Shock Protein HSP60 from Hyperthermophilic Archaeon Pyrococcus furiosus

极端嗜热菌Pyrococcus furiosus热休克蛋白HSP60的克隆表达和纯化

HSPs from hyperthermophilic archaea are concise only with HSP60, sHSP, prefoldin and AAA+proteins, but without HSP100s, HSP90s, HSP70 (DnaK), HSP40 (DnaJ) and GrpE which are common in mesophilic or thermophilic archaea.

随着生物工程产业对于耐高温酶和菌体的需求,极端嗜热古菌热休克蛋白(Heatshock proteins,HSPs)的研究更受重视,其热休克蛋白体系非常简洁,不含HSP100s和HSP90s,就是HSP70(DnaK)、HSP40(DnaJ)和GrpE等嗜温古菌可能含有的在极端嗜热古菌中几乎不含有,即仅包括HSP60、sHSP、prefoldin和AAA+蛋白4大类,因此对其结构、功能和作用机制的研究在理论和实践上都特别有意义。