trisome

Polymerase chain reaction with short tandem repeat(STR-PCR) for the rapid detection of common trisomy;

短串联重复序列聚合酶链反应技术快速诊断常见染色体三体的价值

Clinical and experimental study of 38 cases with trisomy 8;

8号染色体三体38例临床及实验研究

To evaluate the impact of trisomy 8 on cytobiological and clinical features of acute myelomonocytic and monocytic leukemia (M_4, M_5), a total of 56 cases of acute myelomonocytic and monocytic leukemia were investigated.

为了探讨8号染色体三体(8三体)对急性粒单、单核细胞白血病(M4、M5)细胞生物学及临床特征的影响,应用G显带或R显带技术及流式细胞仪对56例M4、M5患者进行核型及免疫表型检测,并对其临床特征进行回顾性分析。

This study was purposed to characterize the first case of acute promyelocitic leukemia (AML-M_3a) with t(15;17) , trisomy 8 and tetrasomy 8,and explore its characteristics of morphology,cytogenetics,molecular biology,immunology and clinical features.

本研究报道首例伴有 8号染色体四体 (四体 8)、8号染色体三体 (三体 8)异常的t(15 ;17)急性早幼粒白血病 (AML M3 a) ,并探讨其形态学、细胞遗传学、分子生物学、免疫学及临床特点。