Dynactin is a multi-subunit complex that has been implicated in the function of cytoplasmic dynein which is a minus end - directed microtubule motor protein with numerous functions including nuclear migration, mitotic spindle orientation, and cytoskeletal reorientation during interphase and mitosis.
动力蛋白激活蛋白(dynactin)是一个与胞浆内动力蛋白的功能相关的多亚基复合物。
BACKGROUND&AIM: Cytoplasmic dynein is a kind of microtubule_based related protein involving in many fundamental cellular process including organelles transport,spindles assembly and spindle checkpoint inactivˉity.
背景与目的 :胞浆Dynein(动力蛋白)做为微管负极方向的马达蛋白在细胞增殖进程中发挥重要作用。
In this study,a dynein light chain gene LC8 was amplified from a cDNA library of human B lymphocyte and inserted to a GFP-expressing vector pEGFP-C3.
动力蛋白是活跃于微管骨架上行使负向运输功能的分子马达。
Dynamitin, the 50 kD subunit of dynactin, is important for stabilizing the dynactin complex.