picrotoxin

2 μg picrotoxin(PTX) was microinjected into the right HPC(RHPC) to induce rat epilepsy.

目的:观察右侧海马(HPC)微量注射印防己毒素(PTX)诱导HPC癫痫电网络重建过程中HPC-体循环动脉血压调节网络的形成。

METHODS: Seizures were induced by intraperitoneal administration of pentylenetetrazol(PTZ), picrotoxin(PIC), or kainic acid(KA) respectively.

方法:采用腹腔注射戊四唑(PTZ),印防己毒素(PIC)或红藻氨酸(KA)诱导的癫痫发作为模型,比较GAT-1转基因小鼠和C57BL/6J对照小鼠阵挛性发作和强直性痉挛发生的百分率及潜伏期。

The mice were pretreated with succinic acid, 30 min later, picrotoxin, a GABAA receptor antagonist was given by ip, then the effects of succinic acid on mice were observe.

测定琥珀酸对GABA_A受体拮抗剂印防己毒素诱发小鼠惊厥的影响。